Check Intently (2)pentobarbital will lessen the extent or impact of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Strong CYP3A4 inducers may possibly decrease suvorexant efficacy; if enhanced suvorexant dose required, never exceed twenty mg/working dayThe use of barbiturates as sedatives in the pos